Multicentric Calcified Trichilemmal Cysts With Alopecia Universalis Affecting Siblings

December 2012 in “ Indian Journal of Dermatology Venereology and Leprology ”

HaneefN Sadath, Srinivas Sulugodu Ramachandra, MettaA Kumar, K Haritha

calcified trichilemmal cysts alopecia universalis genetic link multicentric cyst distribution

TLDR Two sisters had rare, widespread cysts and complete hair loss, suggesting a genetic link.

A 40-year-old female presented with multiple calcified trichilemmal cysts distributed across various body areas, a rare occurrence typically seen as solitary nodules on the scalp, and was associated with alopecia universalis. Her elder sister exhibited similar symptoms, suggesting a genetic link. The case highlighted the unusual combination of multicentric cyst distribution, calcification, familial occurrence, and its association with alopecia universalis, which were considered rare and intriguing features.

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