Minoxidil-Induced Lung Disease Masquerading As Hypersensitivity Pneumonitis

    January 2023 in “ Respiratory Medicine Case Reports
    Daisuke Takekosh, Teruhisa Nemoto, Susumu Saito, Yuma Matsui, Shunsuke Minagawa, Hiromichi Hara, Takanori Numata, Jun Araya, Kazuyoshi Kuwano
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    Studysummary This case report identified drug-induced lung disease caused by minoxidil in a patient initially misdiagnosed with hypersensitivity pneumonitis, stressing the need for accurate medication history. Our plain-language summary of this paper — not a Tressless recommendation.
    A 71-year-old male with essential thrombosis developed lung issues that appeared as ground-glass opacity with a mosaic pattern on a CT scan, initially suspected to be hypersensitivity pneumonitis (HP). However, it was later identified as a drug-induced lung disease caused by minoxidil, which the patient had been taking without disclosure. The condition resolved spontaneously with hospitalization. This case highlighted the critical need for accurate medication history to ensure correct diagnosis and was the first reported instance of minoxidil causing a pulmonary illness resembling HP.
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