Michaelis-Menten Kinetic Modification: Space Pharmaceuticals Bioavailability Approaches Finasteride

    January 2025 in “ Pharmacology &amp Pharmacy
    Hung-Te Henry Su, P Lee
    TLDR Microgravity may increase drug bioavailability, potentially reaching up to 80%.
    The study investigates the impact of microgravity on the bioavailability of pharmaceuticals, using finasteride as a reference. It finds that microgravity can enhance drug reactions through second-order dynamics and quantum tunneling, potentially increasing bioavailability to around 63.2%, similar to finasteride's 63% on Earth. The research suggests that space-manufactured drugs could achieve even higher bioavailability, up to 80%, due to improved solubility and distribution. However, the study notes limitations in microgravity modeling and emphasizes the need for further research to better understand space conditions' effects on drug absorption, metabolism, and efficacy.
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