Do Medications for Benign Prostate Syndrome Affect Mood or Cognition?

    February 2019 in “ Der Urologe ”
    Klaus Becher, Stephan Madersbacher, Martin C. Michel
    TLDR Medications for benign prostatic syndrome can cause cognitive issues and depression.
    The document examined the central nervous side effects of medications for benign prostatic syndrome (BPS), highlighting cognitive impairments and depressive symptoms. It found that muscarinic antagonists were associated with cognitive impairments, though the frequency varied. Depressive symptoms were consistently linked to 5α-reductase inhibitors like dutasteride and finasteride, with a plausible mechanism. A single study noted a moderate increase in dementia diagnoses with tamsulosin, but not with other α1-adrenoceptor antagonists, possibly due to selection bias. The document recommended that physicians monitor for these side effects during BPS treatment.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results

    Related Community Posts Join

    6 / 162 results

      community Massive study on finasteride side effects released

      in Finasteride/Dutasteride  83 upvotes 2 years ago
      The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.
      Can I still save my hairline at age of 15?

      community Can I still save my hairline at age of 15?

      in General  478 upvotes 3 weeks ago
      A 15-year-old is concerned about hair loss, possibly at Norwood 2 or 3, and is using shampoos and conditioners recommended by a trichologist. Suggestions include considering topical minoxidil and consulting a doctor about topical anti-DHT treatments like finasteride or RU58841, but avoiding 5-alpha-reductase inhibitors at this age.

      community Is finasteride better than dutasteride?

      in Finasteride/Dutasteride  31 upvotes 3 months ago
      Dutasteride reduces DHT more effectively than finasteride, but finasteride is more commonly used and approved for hair loss. Users have mixed opinions on dutasteride's effectiveness, with some experiencing better results and others facing side effects or no improvement.

      community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

      in Research/Science  12 upvotes 11 months ago
      Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

    Similar Research

    5 / 1000+ results