Do Medications for Benign Prostate Syndrome Affect Mood or Cognition?

    February 2019 in “ Der Urologe ”
    Klaus Becher, Stephan Madersbacher, Martin C. Michel
    Studysummary This review discusses the risk of central nervous side effects, such as dementia and depression, from drugs used to treat lower urinary symptoms related to benign prostatic hyperplasia, and highlights inconsistent evidence across different medications.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 7

    1. Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition Psychoneuroendocrinology · 2018
    2. The Risk of Dementia with the Use of 5 Alpha Reductase Inhibitors Journal of the neurological sciences · 2017
    3. Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome Skin appendage disorders · 2016
    4. Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain Neuroendocrinology · 2015
    5. Appropriateness of Oral Drugs for Long-Term Treatment of Lower Urinary Tract Symptoms in Older Persons: Results of a Systematic Literature Review and International Consensus Validation Process (LUTS-FORTA 2014) Age and Ageing · 2015
    6. Patients Treated for Male Pattern Hair Loss with Finasteride Show Altered Levels of Neuroactive Steroids in Cerebrospinal Fluid and Plasma After Discontinuation The Journal of Steroid Biochemistry and Molecular Biology · 2014
    7. Side Effects of 5-Alpha Reductase Inhibitors: A Comprehensive Review Sexual medicine reviews · 2013