TLDR Maternal hypothyroidism harms skin development in rat offspring.
The study investigates the effects of maternal subclinical and clinical hypothyroidism on the skin and its derivatives in rat offspring. The research highlights that maternal hypothyroidism can lead to significant alterations in the skin structure and function of the offspring. These changes include impaired hair follicle development and altered skin thickness, which may have long-term implications for the health and well-being of the offspring. The findings underscore the importance of thyroid hormone regulation during pregnancy for the proper development of skin and its derivatives in offspring.
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