From Sea to Therapy: Marine Biomaterials for Drug Delivery and Wound Healing

    July 2025 in “ Pharmaceuticals
    Mansi Chilwant, Valentina Paganini, Mariacristina Di Gangi, Sofía Gisella Brignone, Patrizia Chetoni, Susi Burgalassi, Daniela Monti, Silvia Tampucci
    TLDR Marine biomaterials show promise for drug delivery and wound healing.
    This review explores the potential of marine-derived biomaterials, such as polysaccharides, proteins, and peptides, in drug delivery and wound healing. It discusses the extraction, processing, and pharmaceutical applications of these biopolymers, emphasizing their ability to be engineered into various forms like nanocarriers and hydrogels. Key fabrication methods, including ionic gelation and 3D bioprinting, are analyzed for their effectiveness in drug encapsulation and scaffold design. The review also addresses preclinical validation, scale-up challenges, and regulatory considerations, highlighting emerging technologies like stimuli-responsive biomaterials. It provides a comprehensive guide for developing sustainable and multifunctional pharmaceutical platforms.
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