Chitosan-Based Hemostatic Hydrogels: Concept, Mechanism, Application, and Prospects

Chitosan-based hemostatic hydrogels were explored for their potential in managing uncontrolled bleeding due to their biocompatibility, mechanical properties, and ease of use. These hydrogels worked by absorbing red blood cells and activating platelets, promoting hemostasis. The study reviewed recent advancements in chitosan hydrogels, highlighting their advantages over traditional materials like bandages, which are prone to infection and pain. The paper discussed the impact of factors such as deacetylation degree and chemical modifications on the performance of these hydrogels. Despite the promise of chitosan hydrogels, challenges remained, such as ensuring rapid gelation and maintaining adhesion in dynamic environments. The study concluded with future prospects for improving the efficiency and safety of chitosan-based hemostatic materials.