Chitosan-Based Hemostatic Hydrogels: Concept, Mechanism, Application, and Prospects
February 2023
in “
Molecules
”
Studysummary This review article discusses recent progress in chitosan-based hemostatic hydrogels, highlighting their unique properties, such as biocompatibility and enhanced hemostatic performance, compared to traditional materials. The authors summarize their hemostatic mechanisms and future potential in improving emergency bleeding control.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Chitosan-based hemostatic hydrogels were explored for their potential in managing uncontrolled bleeding due to their biocompatibility, mechanical properties, and ease of use. These hydrogels worked by absorbing red blood cells and activating platelets, promoting hemostasis. The study reviewed recent advancements in chitosan hydrogels, highlighting their advantages over traditional materials like bandages, which are prone to infection and pain. The paper discussed the impact of factors such as deacetylation degree and chemical modifications on the performance of these hydrogels. Despite the promise of chitosan hydrogels, challenges remained, such as ensuring rapid gelation and maintaining adhesion in dynamic environments. The study concluded with future prospects for improving the efficiency and safety of chitosan-based hemostatic materials.
