TLDR A rare scalp condition was successfully treated with specific medications after 9 months.
Erosive pustular dermatosis of the scalp (EPDS) is a rare, chronic condition characterized by pustular, erosive, and crusted lesions leading to scarring alopecia. The exact cause is unknown, but factors like local trauma, skin grafting, and sun exposure are implicated. A 22-year-old Asian man with an 8-year history of scalp pustules and crusts was diagnosed with EPDS based on clinical and histologic findings. Treatment with topical tacrolimus and oral isotretinoin led to resolution after 9 months. EPDS is challenging to diagnose and treat due to its rarity, and no standard treatment exists, though various medications have shown potential.
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