<I>Hoxc13</I> and the development of hair follicle

August 2010 in “ Hereditas (Beijing) ”

Jianghong Wu, Z.W. Yan, sile Hu, Wenguang Zhang, Jinquan Li

Hoxc13 hair follicle keratin keratin-associated proteins Hox gene family

TLDR Hoxc13 is essential for hair growth and follicle development.

Hoxc13, a gene from the Abd-B class of the Hox gene family, played a crucial role in hair follicle formation and hair growth regulation. It regulated the expression of keratin (KP) and keratin-associated proteins (KAP), which are structural proteins of hair, thereby influencing hair characteristics and maintaining normal hair follicle morphology. The review summarized the relationship between Hoxc13 expression levels and hair follicle development and growth, as well as the mechanisms controlled by Hoxc13 and related genes.

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