TLDR Lower Gas6 and sAxl levels are linked to hair loss in COVID-19 survivors.
In a study involving 263 COVID-19 survivors, researchers found that decreased plasma levels of Growth Arrest-Specific 6 (Gas6) and its soluble receptor Axl (sAxl) were associated with hair loss. Of the participants, 69 (26.2%) experienced hair loss, with Gas6 and sAxl levels, along with female sex, being independent predictors. Although most cases resolved spontaneously, 23.7% of subjects reported persistent hair loss one year post-discharge. The study highlights the potential role of Gas6 and sAxl in post-COVID-19 hair loss.
25 citations
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February 2022 in “JAAD International” Some COVID-19 patients lose hair, with the most common type linked to male hormones and possibly increasing the risk of severe illness.
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February 2022 in “JAAD International” COVID-19 may be linked to hair loss or worsening of hair loss in some people.
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October 2021 in “Signal Transduction and Targeted Therapy” Stress hormone corticosterone suppresses hair growth by affecting stem cell activity and Gas6 protein expression.
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August 2021 in “Scientific Reports” COVID-19 leaves 80% of patients with long-term symptoms like fatigue and headaches.
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March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
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January 2021 in “Dermatologic Therapy” COVID-19 may cause hair loss due to infection stress or treatments.
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February 2023 in “Materials today bio” The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
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October 2020 in “Experimental Dermatology” Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
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April 2023 in “Cureus” Stem cells could be a better treatment for hair loss by reactivating dormant hair follicles.
