Jxl069 (pp405 api) week 8 update
    Progress Pictures 8/15/2025

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    ๐Ÿ’ง JXL-069 (topical) 8 weeks
    ๐Ÿ’Š Finasteride (oral) over 2 years
    ๐Ÿ’ง Minoxidil (topical) over 2 years
    the tone is ๐Ÿ˜ neutral with minimal results.
    The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.
    View this post in the Community โ†’

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    5 / 7 results

      community The Fear of Oral Minoxidil is Overblown

      in Research/Science  227 upvotes 1 month ago
      Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.

      community PP405 Phase 2a press release with early results

      in Research/Science  696 upvotes 2 months ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Is PP405 formula available in grey market?

      in Treatment  15 upvotes 6 months ago
      The conversation is about the availability of the PP405 formula for hair loss treatment, with mentions of finasteride and its side effects. Users discuss the potential of obtaining the formula through unofficial channels and the challenges related to its genetic sequence and delivery method.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 4 days ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

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