Long-Term Evaluation of Efficacy and Safety of Finasteride in Japanese Men with Androgenetic Alopecia: Summary of Three Investigations

July 2022 in “ Hair transplant forum international ”

Masayuki Yanagisawa, Akio Sato

finasteride androgenetic alopecia hair growth disease progression adverse reactions Post Finasteride Syndrome Propecia AGA

TLDR Finasteride is effective and safe for long-term use in treating hair loss in Japanese men.

Long-term treatment (over 10 years) with finasteride 1 mg/day in Japanese men with androgenetic alopecia (AGA) has shown high efficacy and safety. Three large-scale investigations (3,177 cases over 2.5 years, 801 cases over 5 years, and 532 cases over 10 years) demonstrated significant improvement in hair growth and prevention of disease progression, particularly in early-stage AGA patients and those younger than 40 years. Adverse reactions were minimal, with rates of 0.7% over 2.5 years and 6.8% over 10 years, and no cases of Post Finasteride Syndrome were reported.

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Research cited in this study

8 / 8 results

research Long-Term (10-Year) Efficacy of Finasteride in 523 Japanese Men with Androgenetic Alopecia

8 citations , January 2019 in “Clinical research and trials”

Finasteride is effective and safe for long-term treatment of hair loss in Japanese men.

research Five-Year Efficacy of Finasteride in 801 Japanese Men with Androgenetic Alopecia

13 citations , April 2015 in “Journal of Dermatology”

Finasteride effectively promotes hair growth and reduces hair loss in men with androgenetic alopecia.

research Evaluation of Efficacy and Safety of Finasteride 1 mg in 3177 Japanese Men with Androgenetic Alopecia

41 citations , October 2011 in “Journal of Dermatology”

Finasteride 1 mg effectively and safely increases hair growth in Japanese men with hair loss.

research Finasteride, 1 Mg Daily Administration on Male Androgenetic Alopecia in Different Age Groups: 10-Year Follow-Up

44 citations , July 2011 in “Dermatologic Therapy”

Finasteride effectively increases hair growth in men with AGA, works better for those over 30, and may cause some side effects.

research Androgens and Alopecia

165 citations , December 2002 in “Molecular and Cellular Endocrinology”

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

research The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia

65 citations , October 1999 in “Journal of The American Academy of Dermatology”

Finasteride effectively reduces hair loss by decreasing androgen levels.

research Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia

32 citations , April 1999 in “Expert Opinion on Investigational Drugs”

Finasteride effectively treats male hair loss, improving growth and density.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations , October 1998 in “Journal of The American Academy of Dermatology”

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

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