Long-Term Evaluation of Efficacy and Safety of Finasteride in Japanese Men with Androgenetic Alopecia: Summary of Three Investigations

    July 2022 in “ Hair transplant forum international ”
    Masayuki Yanagisawa, Akio Sato
    TLDR Finasteride is effective and safe for long-term use in treating hair loss in Japanese men.
    Long-term treatment (over 10 years) with finasteride 1 mg/day in Japanese men with androgenetic alopecia (AGA) has shown high efficacy and safety. Three large-scale investigations (3,177 cases over 2.5 years, 801 cases over 5 years, and 532 cases over 10 years) demonstrated significant improvement in hair growth and prevention of disease progression, particularly in early-stage AGA patients and those younger than 40 years. Adverse reactions were minimal, with rates of 0.7% over 2.5 years and 6.8% over 10 years, and no cases of Post Finasteride Syndrome were reported.
    Discuss this study in the Community →

    Research cited in this study

    8 / 8 results

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Anyone else growing tired of the finasteride wars?

      in Finasteride/Dutasteride  169 upvotes 1 year ago
      The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community How uninformed the general public is about hair loss

      in Chat  313 upvotes 9 months ago
      The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

    Related Research

    3 / 3 results