Long-Term Evaluation of Efficacy and Safety of Finasteride in Japanese Men with Androgenetic Alopecia: Summary of Three Investigations

    Masayuki Yanagisawa, Akio Sato
    TLDR Finasteride is effective and safe for long-term use in treating hair loss in Japanese men.
    Long-term treatment (over 10 years) with finasteride 1 mg/day in Japanese men with androgenetic alopecia (AGA) has shown high efficacy and safety. Three large-scale investigations (3,177 cases over 2.5 years, 801 cases over 5 years, and 532 cases over 10 years) demonstrated significant improvement in hair growth and prevention of disease progression, particularly in early-stage AGA patients and those younger than 40 years. Adverse reactions were minimal, with rates of 0.7% over 2.5 years and 6.8% over 10 years, and no cases of Post Finasteride Syndrome were reported.
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