Basic Hair Transplantation: 2007

    December 2007 in “ Dermatologic Therapy
    Neil S. Sadick, Michael P. White
    From the encyclopedia
    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    Hair Transplant →

    Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

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    Studysummary This review discusses past hair transplantation techniques for androgenic alopecia and current research to improve results, but it reports no new clinical outcomes.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    In the 2007 review on hair transplantation, the authors discussed the evolution of techniques from large grafts to mini- and micrografting, and the significant advancement of follicular unit transplantation (FUT) since 1995. They emphasized the importance of minimizing follicle transection and explored new harvesting methods to improve donor yield. The review also suggested that preconditioning grafts with storage buffers could enhance survival. A study by Raposio et al. involving 10 subjects found no significant difference in graft survival between room temperature and cooled micrografts. Another study by Bernstein and Rassman with 42 patients showed that grafts are securely anchored by day 9 post-transplantation. Follicular unit extraction (FUE) was discussed as a less invasive option, with a study of five patients indicating the survival rate of transected follicles depends on the level of transection. The document also covered the use of minoxidil post-surgery to enhance growth, the potential of spironolactone and flutamide in preventing post-transplant hair loss, and the importance of graft orientation and recipient site characteristics for natural-looking results. Additionally, it discussed donor site closure techniques and the need for patient satisfaction with results. Overall, the document highlighted the progression towards more natural results and the critical role of technique in graft survival and patient satisfaction.
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