A Method to Monitor Dutasteride in Rat Plasma Using Liquid-Liquid Extraction and Multiple Reaction Monitoring: Comparisons and Validation

    September 2014 in “ Mass spectrometry letters ”
    Myung Joo Kang, Ha Ra Cho, Dong Hoon Lee … Yong Seok Choi
    Studysummary This study reported that a liquid-liquid extraction method using methyl tert-butyl ether and methylene chloride was most effective for extracting dutasteride and its internal standard from rat plasma.
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    Research cited in this study 2

    1. Rapid and Sensitive LC-MS-MS Method for the Simultaneous Estimation of Alfuzosin and Dutasteride in Human Plasma Chromatographia · 2008
    2. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006