Pharmacokinetics and Bioconversion of Dehydroepiandrosterone After Dexamethasone Application in Women with Polycystic Ovary Syndrome

January 2004 in “ Online Publication Service of Würzburg University (Würzburg University) ”

Schlenz, Nadine

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dehydroepiandrosterone DHEA dexamethasone polycystic ovary syndrome PCOS 5alpha-Dihydrotestosterone DHT 5alpha-reductase androstendion testosterone steroid biosynthesis

Studysummary This study found that women with PCOS displayed significantly higher activity of 5alpha-reductase, suggesting an additional role for liver and peripheral tissues in their androgen excess.

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