Investigative guidelines for alopecia areata

    May 2011 in “ Dermatologic therapy
    Elise A. Olsen
    TLDR Guidelines help design better trials to compare alopecia areata treatments.
    The document discussed the challenges in comparing the efficacy of various treatments for alopecia areata due to the lack of consideration for spontaneous regrowth, baseline prognostic factors, and quantification of hair growth in case reports and clinical trials. It provided guidelines for clinical trial design that accounted for variables like baseline severity, pattern, duration of hair loss, age, and concomitant conditions. The report also covered reliable methods for assessing efficacy and response criteria to enable direct comparison of results between different treatments.
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