Efficiency Assessment of Intralesional Platelet-Rich Plasma Therapy for Scalp Alopecia Areata: A Randomized Comparative Single-Blinded Study

January 2024

Varsha Jamale, Fatima Sanjeri Dasankoppa, Ritesh Kumar Shah, Rohan S. Phatak

intralesional platelet-rich plasma alopecia areata scalp alopecia hair regrowth PRP

TLDR PRP therapy significantly regrows hair and satisfies patients without side effects.

This study evaluated the efficiency of intralesional platelet-rich plasma (PRP) therapy for scalp alopecia areata in a randomized comparative single-blinded design over 24 weeks. Participants were unaware of their group assignments, and hair regrowth was assessed at baseline and every 12 weeks. The findings indicate that intralesional PRP therapy leads to significant hair regrowth and increased patient satisfaction, with no notable adverse effects.

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Research cited in this study

6 / 6 results

research A Case of Unusual Comedogenesis in Alopecia Totalis

June 2022 in “Indian Dermatology Online Journal”

A man with total hair loss developed blackhead-like spots on his scalp, possibly because no hair was present to help drain oils.

research The Effect of Platelet-Rich Plasma on Hair Regrowth in Patients with Alopecia Areata Totalis: A Clinical Pilot Study

14 citations , June 2019 in “Dermatologic therapy”

PRP did not significantly regrow hair in alopecia areata totalis patients.

research Epidemiology and Burden of Alopecia Areata: A Systematic Review

144 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

Comparative Study of Efficacy of Excimer Light Therapy vs. Intralesional Triamcinolone vs. Topical 5% Minoxidil for Alopecia Areata: An Observational Study

research Comparative Study of Efficacy of Excimer Light Therapy vs. Intralesional Triamcinolone vs. Topical 5% Minoxidil for Alopecia Areata: An Observational Study

January 2015 in “Przegla̧d dermatologiczny”

Intralesional triamcinolone is the most effective treatment for alopecia areata, followed by excimer light therapy, and then topical minoxidil. The scalp responds better to treatment than the beard area.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , April 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research Intralesional Steroids for Alopecia Areata

36 citations , January 2010 in “International Journal of Trichology”

Intralesional steroids can help regrow hair in some alopecia areata patients but have side effects.

Related Research

2 / 2 results

research Serum Zinc Concentration in Patients With Alopecia Areata

October 2023 in “Acta dermato-venereologica (Print)”

People with severe hair loss have lower zinc levels in their blood.

research Platelet-Rich Plasma (PRP) as a New Approach and Promising Therapy in Patients With Alopecia Areata

March 2023 in “Medica Hospitalia: Journal of Clinical Medicine”

PRP is a safe and effective treatment for hair growth in alopecia areata.