Efficiency Assessment of Intralesional Platelet-Rich Plasma Therapy for Scalp Alopecia Areata: A Randomized Comparative Single-Blinded Study

January 2024

Varsha Jamale, Fatima Sanjeri Dasankoppa, Ritesh Kumar Shah, Rohan S. Phatak

intralesional platelet-rich plasma alopecia areata scalp alopecia hair regrowth PRP

From the encyclopedia

autoimmune disorder causing patchy hair loss

growth factors taken from your blood and injected into your scalp to stimulate hair

Studysummary This study provides evidence that intralesional platelet-rich plasma therapy leads to significant hair regrowth and increased patient satisfaction in individuals with scalp alopecia areata over 24 weeks, without notable adverse effects.

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This study evaluated the efficiency of intralesional platelet-rich plasma (PRP) therapy for scalp alopecia areata in a randomized comparative single-blinded design over 24 weeks. Participants were unaware of their group assignments, and hair regrowth was assessed at baseline and every 12 weeks. The findings indicate that intralesional PRP therapy leads to significant hair regrowth and increased patient satisfaction, with no notable adverse effects.

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Research cited in this study

6 / 6 results

research A Case of Unusual Comedogenesis in Alopecia Totalis

June 2022 in “Indian Dermatology Online Journal”

This case report describes a 19-year-old male with alopecia totalis and comedones over the bald scalp, suggesting the importance of terminal hair for sebum drainage to prevent preliminary acne lesions.

research The Effect of Platelet-Rich Plasma on Hair Regrowth in Patients with Alopecia Areata Totalis: A Clinical Pilot Study

14 citations , June 2019 in “Dermatologic therapy”

This study found that autologous platelet-rich plasma injections showed no significant effect on hair regrowth in patients with alopecia areata totalis.

research Epidemiology and Burden of Alopecia Areata: A Systematic Review

144 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”

This review reports that alopecia areata affects about 2% of people globally and is linked with psychiatric and medical comorbidities, highlighting its significant disease burden.

Comparative Study of Efficacy of Excimer Light Therapy vs. Intralesional Triamcinolone vs. Topical 5% Minoxidil for Alopecia Areata: An Observational Study

research Comparative Study of Efficacy of Excimer Light Therapy vs. Intralesional Triamcinolone vs. Topical 5% Minoxidil for Alopecia Areata: An Observational Study

January 2015 in “Przegla̧d dermatologiczny”

This study observed that excimer light therapy, intralesional triamcinolone, and topical 5% minoxidil all had differing levels of effectiveness in treating alopecia areata, with variable results noted among treatments.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , April 2013 in “British Journal of Dermatology”

In this study, platelet-rich plasma significantly increased hair regrowth and reduced symptoms of alopecia areata compared to triamcinolone acetonide or placebo, with no observed side effects.

research Intralesional Steroids for Alopecia Areata

36 citations , January 2010 in “International Journal of Trichology”

Intralesional steroids can help regrow hair in some alopecia areata patients but have side effects.