Effect of Inhibiting Prolactin Secretion on Secondary Hair Follicle Development in Cashmere Goats

May 2025 in “ Animal Bioscience ”

Chunhui Duan, Xuejiao Yin, Kexing Hao, Lechao Zhang, Yuchun Xie, Xueru Li, Yueqin Liu, Yingjie Zhang

prolactin secondary hair follicle Kit gene telogen phase hair bulb Fos activation

TLDR Inhibiting prolactin reduces hair follicle activation in cashmere goats.

The study investigates the role of prolactin (PRL) in secondary hair follicle (SHF) development in cashmere goats, focusing on the Kit gene's mediation of PRL's effects. It was found that inhibiting PRL secretion during the telogen phase can lead to a reduction in the number of activated SHFs and a decrease in the width of hair bulbs. This suggests that PRL plays a significant role in SHF activation, with the Kit gene and Fos activation being key components in this regulatory process.

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