Determination of Illegally Added Minoxidil in Herbal Hair Growth Cosmetics by HPLC

January 2014 in “ Food and Drug ”

Gong Yue-qian

minoxidil herbal hair growth cosmetics High-Performance Liquid Chromatography HPLC Rogaine

TLDR The method accurately detects illegal minoxidil in herbal hair products.

The study aimed to establish a method for detecting illegally added minoxidil in herbal hair growth cosmetics using High-Performance Liquid Chromatography (HPLC). The method utilized a Shimadzu Shim-pack VP-ODS column with a methanol-water mobile phase, achieving a flow rate of 1.0 mL/min and a detection wavelength of 231 nm at a column temperature of 35 ℃. The linear range for minoxidil detection was 0.201-50.360 μg/mL with a correlation coefficient (r) of 0.9999. The method demonstrated average recoveries of 101.7%, 96.9%, and 96.6% with relative standard deviations (RSD) of 2.5%, 1.3%, and 1.3% respectively, indicating that the method was accurate, reliable, and sensitive.

View this study on en.cnki.com.cn →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Exploring Bryan Johnson's Hair Routine In Detail

in Research/Science 65 upvotes 10 months ago

Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

community Melatonin a possible tool to help fight AGA hair loss.

in Research/Science 54 upvotes 3 years ago

Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

community Anyone here going the “natural” route?

in Scalp Massage 48 upvotes 2 years ago

People discussing their experiences with natural treatments for hair loss, such as essential oils, deep scalp massages, anti-inflammatory measures, and supplements. Most of the replies suggest that these treatments are not effective and recommend medication such as minoxidil or finasteride instead.

community Two months of dutasteride once a day 0.5 and minoxidil 5% twice a day. The light is different but I think there is progress

in Is this regrowth? 96 upvotes 1 year ago

A user's experience with taking dutasteride and minoxidil for hair loss, with other users providing advice to continue treatment for at least 12 months and including dermarolling as well as dietary changes.

community I’m 14 years old and I’m losing more hair than my dad. I’ve gone to the doctor 2 times because of this and I’ve received no help. I’m starting to feel like It’s worthless and my hairs gonna look like this forever. I don’t know how anyone could help me but it’s always worth a shot.

in Treatment 4 years ago

A 14 year old who is experiencing hair loss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hair loss such as minoxidil, finasteride, RU58841 and addressing the cause of the hair loss.

community Tropical growth stimulants other than minoxidil

in Treatment 11 upvotes 5 months ago

The conversation discusses alternative hair growth treatments to minoxidil, including Stemoxydine, Tretinoin, adenosine, Baicalin, castor oil, Latanoprost/bimatoprost, and Redensyl. Users share their experiences and opinions on the efficacy of these treatments.