Hypervitaminosis A in a Patient with Alopecia Receiving Renal Dialysis

    July 1979 in “ Archives of Dermatology ”
    E. Shmunes
    TLDR Patients with renal disease should be cautious with vitamin A supplements due to risk of toxicity.
    A patient undergoing long-term renal dialysis experienced gradual hair loss and was found to have a serum vitamin A level of 140 μg/dL, significantly higher than the normal range of 20 to 80 μg/dL. Despite only consuming vitamin A through conventional multivitamins for about three years, the patient exhibited signs of hypervitaminosis A, a condition exacerbated by chronic renal disease and the inability of dialysis to effectively remove vitamin A. The study discussed the implications of administering low-dose vitamin A supplements in patients with renal disease, considering the altered vitamin A metabolism in such conditions.
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