Histopathological Diagnosis of Alopecia Clinically Relevant to Alopecia Areata

February 2023 in “ Siriraj Medical Journal ”

Chinmanat Lekhavat, Pinyo Rattanaumpawan, Antonella Tosti, Tarinee Korviriyakamol, Suthep Jerasutat, Poonnawis Sudtikoonaseth, Penvadee Pattanaprichakul

Alopecia Areata lichen planopilaris lupus panniculitis scarring alopecia terminal telogen hairs vellus hairs follicular streamers nanogen hairs AA

TLDR Not all cases with typical signs of Alopecia Areata are actually diagnosed as such.

A cross-sectional study of 113 patients with typical manifestations of Alopecia Areata (AA) was conducted to study the histopathological diagnosis of AA and compare the histopathology between acute and chronic AA. Out of the 113 patients, 109 (96.5%) were pathologically diagnosed with AA, while others were diagnosed with lichen planopilaris, lupus panniculitis, and unspecified scarring alopecia. The study found that acute AA had a significantly higher percentage of terminal telogen hairs and vellus hairs, while chronic AA had a significantly higher number of follicular streamers and nanogen hairs. The study concluded that typical manifestations of AA are not always diagnosed as AA.

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