Prevalence and Predictors of Hair Shedding Among GLP-1 Receptor Agonist Users: A Cross-Sectional Study from Saudi Arabia

    January 2026 in “ Skin Appendage Disorders ”
    Sali Alharbi, Azzam Alkhalifah
    Studysummary This study found that hair shedding occurs in seven out of ten users of GLP-1 receptor agonists in real-world settings, a much higher prevalence than in clinical trials, which affects treatment adherence, especially among women experiencing significant weight loss.
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    Research cited in this study 12

    1. Risk of Alopecia Areata with Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss medRxiv (Cold Spring Harbor Laboratory) · 2025
    2. Dermatologic Implications of GLP-1 Receptor Agonist Medications: A Comprehensive Review Skin Appendage Disorders · 2025
    3. Exploring the Hair Loss Risk in Glucagon-Like Peptide-1 Agonists: Emerging Concerns and Clinical Implications Journal of the European Academy of Dermatology and Venereology · 2025
    4. Risk of Suicide, Hair Loss, and Aspiration with GLP1-Receptor Agonists and Other Diabetic Agents: A Real-World Pharmacovigilance Study Cardiovascular Drugs and Therapy · 2024
    5. Telogen Effluvium in Patients After Bariatric Surgery: A Scoping Review Brazilian Journal of Clinical Medicine and Review · 2024
    6. GLP-1 Agonists and Hair Loss: A Call for Further Investigation International Journal of Dermatology · 2024
    7. Association of Obesity and Bariatric Surgery on Hair Health Medicina-lithuania · 2024
    8. Bariatric Surgery-Induced Telogen Effluvium (Bar SITE): Case Report and Review of Hair Loss Following Weight Loss Surgery Cureus · 2021
    9. Hair Loss After Metabolic and Bariatric Surgery: A Systematic Review and Meta-Analysis Obesity surgery · 2021
    10. The Role of Vitamins and Minerals in Hair Loss: A Review Dermatology and Therapy · 2018
    11. Diet and Hair Loss: Effects of Nutrient Deficiency and Supplement Use Dermatology practical & conceptual · 2017
    12. Stress Inhibits Hair Growth in Mice by Inducing Premature Catagen Development and Harmful Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003