Effect of Haegimsa (Lygodium Japonicum) on Prostate Enlargement in Rats

    이두현, 이장식, 김용성
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    Studysummary This study suggests that Lygodium japonicum may reduce cell damage and tissue proliferation in a rat model of benign prostatic hyperplasia, indicating potential as a treatment.
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    The study investigated the effects of Lygodium japonicum on benign prostatic hyperplasia (BPH) in a rat model. BPH was induced in Sprague-Dawley rats through castration and testosterone treatment. Lygodium japonicum was administered orally, with finasteride as a positive control. Results showed that Lygodium japonicum reduced damage to luminal and duct epithelial cells and decreased stromal and connective tissue proliferation compared to the control group. The study concluded that Lygodium japonicum could protect glandular epithelial cells and may be a useful treatment for BPH.
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