Effects of Phellodendron Bark on Prostatic Hyperplasia in Rats

    박정준, 이장식, 김용성
    TLDR Phellodendri Cortex Extract may help treat benign prostatic hyperplasia.
    The study investigated the effects of Phellodendri Cortex Extract on benign prostatic hyperplasia (BPH) in rats, which was induced by castration and testosterone treatment. The results showed that Phellodendri Cortex Extract reduced tissue damage in the prostate and inhibited the expression of 5α-reductase genes, similar to the effects of Finasteride, a known BPH treatment. These findings suggested that Phellodendri Cortex Extract could protect glandular epithelial cells and inhibit stromal proliferation, indicating its potential as a therapeutic agent for BPH.
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