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    Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring

    July 2019 in “ Cardiovascular Research ”
    Maria Manti, Romina Fornes, Gianluigi Pironti … Elisabet Stener-Victorin
    Studysummary This study found that prenatal exposure to androgens caused long-lasting heart remodeling and left ventricular hypertrophy in female mice offspring, suggesting potential cardiac risks for daughters of mothers with PCOS.
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    Research cited in this study 3

    1. Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction Circulation · 2015
    2. Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society The Journal of Clinical Endocrinology & Metabolism · 2010
    3. Polycystic Ovary Syndrome: Comprehensive Overview and Diagnostic Criteria The Lancet · 2007

    Related research 1

    1. Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring Cardiovascular Research · 2019