Extracellular Vesicles From IFN-γ-Primed Mesenchymal Stem Cells Repress Atopic Dermatitis In Mice

    December 2022 in “ Journal of Nanobiotechnology
    Jimin Kim, Seul Ki Lee, Minyoung Jung, Seon‐Yeong Jeong, Haedeun You, Ji‐Yeon Won, Sang-Deok Han, Hye Jin Cho, Somi Park, Joonghoon Park, Tae Min Kim, Soo Kim
    Studysummary In this study, IFN-γ-stimulated iPSC-derived mesenchymal stem cell extracellular vesicles improved atopic dermatitis in mice by reducing Th2 cytokine activity, suppressing inflammation, and restoring skin barrier function, as evidenced by decreased itching and inflammatory markers.
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