Extracellular Vesicles From IFN-γ-Primed Mesenchymal Stem Cells Repress Atopic Dermatitis In Mice

    December 2022 in “ Journal of Nanobiotechnology ”
    Jimin Kim, Seul Ki Lee, Minyoung Jung … Soo Kim
    Studysummary In this study, IFN-γ-stimulated iPSC-derived mesenchymal stem cell extracellular vesicles improved atopic dermatitis in mice by reducing Th2 cytokine activity, suppressing inflammation, and restoring skin barrier function, as evidenced by decreased itching and inflammatory markers.
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    Research cited in this study 1

    1. Mesenchymal Stem/Stromal Cell Therapy in Atopic Dermatitis and Chronic Urticaria: Immunological and Clinical Viewpoints Stem Cell Research & Therapy · 2021