Evaluation of apoptosis regulatory markers in androgenetic alopecia
December 2010
in “Journal of Cosmetic Dermatology”
TLDR Apoptosis may contribute to hair loss in androgenetic alopecia.
This study evaluated the role of apoptosis regulatory markers in androgenetic alopecia (AGA) by examining the expression of various markers in the hair follicles of AGA patients and normal controls. The study found that the bald area of AGA has a lower proliferation rate and increased DNA damage, which may result in increased apoptosis and follicular miniaturization. The study suggests that apoptosis may play a role in the pathogenesis of AGA, but further studies are needed to confirm this.
View this study on onlinelibrary.wiley.com →
Cited in this study
research Androgenetic alopecia in males: a histopathological and ultrastructural study
Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.
research Proliferation, DNA repair and apoptosis in androgenetic alopecia
Bald areas have lower cell growth, more DNA damage, and increased cell death.
research The hair cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
research Aging of hair
Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
research Hair shape of curly hair
Curly hair shape is determined by the hair bulb.
research Androgenetic Alopecia: Analysis of Proliferation and Apoptosis
research An Investigation of Apoptosis in Androgenetic Alopecia
Apoptosis contributes to hair loss in androgenetic alopecia.
research p53 Involvement in the Control of Murine Hair Follicle Regression
The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
research Apoptosis and cutaneous biology
Apoptosis is crucial for healthy skin and treating skin diseases.
Related
research Evaluation of apoptosis regulatory markers in androgenetic alopecia
Apoptosis may contribute to hair loss in androgenetic alopecia.