Estimation of Serum Prostaglandin D2 Levels and Its Expression in Tissue of Alopecia Areata

    December 2019 in “ Fayoum University Medical Journal ”
    Talal Abd-ElRaheem, Samar El-Tahlawy, Olfat Shaker, Mohamed Mohamed, Yasmin Soliman
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    Studysummary This study reported that prostaglandin D2 levels were significantly lower in both the serum and tissue of Egyptian patients with alopecia areata compared to healthy controls.
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    In 2019, researchers Abd-ElRaheem, El-Tahlawy, Shaker, Mohamed, and Soliman conducted a study to estimate the levels of serum prostaglandin D2 and its expression in the tissue of individuals with Alopecia areata. The study found that there was a significant increase in the levels of serum prostaglandin D2 in patients with Alopecia areata compared to the control group. Additionally, the expression of prostaglandin D2 in the tissue of these patients was also significantly higher. These findings suggest that prostaglandin D2 may play a role in the pathogenesis of Alopecia areata.
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