July 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)” This article reviews the effects of minoxidil on hair growth, highlighting its ability to stimulate hair follicle proliferation, but reports no new clinical findings.
7 citations
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May 2013 in “PubMed” In this randomized, placebo-controlled study, the tested cosmetic ingredient containing Trifolium pratense flower extract and a biomimetic peptide increased anagen hair and improved the anagen/telogen ratio over four months in individuals with recessing hair.
37 citations
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October 2009 in “Dermatology” This study suggests that the action of minoxidil in stimulating hair growth likely occurs at the follicular dermal papilla, though it does not induce new follicle formation.
January 2008 in “Acta Anatomica Sinica” In this study, minoxidil promoted hair follicle growth in culture by delaying catagen phase onset and possibly inhibiting TGFβ1 overexpression.
24 citations
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January 2006 in “Skin Pharmacology and Physiology” This study found that finasteride (1 mg/day) appeared to reverse the shortening of the hair cycle in androgen sensitive sites but did not convert miniaturized hair into terminal hair.
30 citations
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September 2004 in “Experimental Dermatology” This study found that minoxidil did not significantly increase hair shaft elongation in ex vivo human hair follicle culture, questioning the suitability of this method for studying its hair-growth-promoting effects.
24 citations
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September 2001 in “Journal of Dermatological Science” This study found that cyclophosphamide-induced hair follicle damage in C3H mice could be remodelled into intact anagen hair follicles with topical cyclosporin A, especially in anagen IV stage follicles.
3 citations
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June 1997 in “Veterinary Dermatology” In this study, daily topical minoxidil treatment in neonatal hairless pups led to increased hair growth and the development of hair follicles in the treated areas.
1 citations
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January 1992 in “Juntendō Igaku/Juntendo igaku” This review discusses the hair growth mechanisms of minoxidil, suggesting both increased blood flow and a direct effect on hair follicles, but reports no new clinical results.
September 1990 in “Journal of Dermatological Science” 8 citations
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January 1989 in “PubMed” This study found that applying minoxidil topically had no recognizable effect on hair follicle growth in newborn mice, though it highlighted apoptosis as a potential marker for hair regression research.
21 citations
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October 1988 in “Clinics in Dermatology” This study found that topical minoxidil induced hair regrowth in stumptailed macaques, with more significant effects observed in younger animals, while cessation led to renewed balding and retreatment restored regrowth.
38 citations
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October 1988 in “Clinics in Dermatology” Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.
78 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth but stops working when discontinued.
6 citations
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January 1981