Reply to 'What Is the Effect of Obesity on the Folliculosebaceous Unit?'

In the document, the authors discuss the findings of Mirmirani and Carpenter's population-based study on the association between obesity and hair-related conditions such as androgenetic alopecia (AGA) and hirsutism in children and adolescents. They highlight that while obesity was linked to hirsutism, it was not associated with AGA in the younger population. However, in their own study, they found a positive correlation between the degree of obesity and the severity of AGA in adult men. The authors suggest that genetic susceptibility is a key factor in AGA pathogenesis, and that hirsutism is usually related to androgen excess, particularly in women. They also note that obesity-related changes in metabolic factors might influence the development of AGA or hirsutism. The authors conclude that the question of how obesity affects the folliculosebaceous unit is complex and requires further investigation into the interactions between genetic, hormonal, metabolic, and nutritional factors.