Dermatological Manifestations and Associated Factors in Patients with Graves' Disease in Dakar

    November 2024 in “ IP Indian Journal of Clinical and Experimental Dermatology ”
    Assane Diop, S. Diadié, Mame Téné Ndiaye, Moustapha Faye, Ismail Tounsi, A Seck, Demba Diédhiou, Boubacar Ahi Diatta, Maodo Ndiaye, Abdoulaye Léye, Fatimata Ly, Suzanne Oumou Niang
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    TLDR Graves' disease often causes skin issues, especially hyperpigmentation, which may be linked to treatments.
    This study investigated the dermatological manifestations in 288 patients with Graves' disease in Dakar, revealing that 72.9% exhibited skin-related symptoms. The most common issues were palmar and/or plantar hyperpigmentation (55.7%), dry and brittle hair (47.6%), and non-scarring alopecia (45%). A significant finding was the correlation between pruritus and oral phytotherapy (p=0.04784), as well as cutaneous hyperpigmentation with carbimazole (p=0.03721) and propranolol (p=0.009850). The study highlights that cutaneous hyperpigmentation is a primary feature of Graves' disease, with some manifestations potentially linked to treatments.
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