Dermatological Manifestations Associated With COVID-19 and COVID-19 Vaccination: Results From the Lebanese COVID Registry

    Remie Chrabieh, Isabelle Haddad, Pascale Salameh, Mazen Kurban, Elio Kechichian, Maya Habre, N. Ayoub, Gretta Torbey, F. El Sayed, Micheline Maamari, Zeina Tannous, Anna Farra, Jinane El Khoury
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    TLDR COVID-19 and its vaccines can cause various skin issues, with urticaria being the most common.
    The study "Dermatological manifestations associated with COVID‐19 and COVID‐19 vaccination: results from the Lebanese COVID registry" conducted an observational cross-sectional study on 142 patients (133 adults and 9 pediatric patients) from May 2021 to May 2022. The main dermatological manifestations reported with COVID-19 infection in the adult group were urticaria (32.9%), telogen effluvium (21.4%), morbilliform (10%), and papulosquamous (8.6%) eruptions. Urticaria was also the most common adverse cutaneous reaction to the vaccine (33%). Interestingly, herpes zoster was triggered in 12 patients post vaccination, more frequently seen in patients above the age of 41 (P = 0.013). In the pediatric group, the most reported dermatological findings associated with COVID-19 infection were malar erythema (25%) and telogen effluvium (25%). One 16-year-old patient developed lichen planus after one dose of a COVID-19 vaccine. No deaths were reported in both age groups. The study concludes that the clinical manifestations of the COVID-19 virus and vaccine are diverse, and more studies are necessary to establish the pathophysiology of these dermatological findings.
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