TLDR Intralesional steroids are the most effective treatment for alopecia areata.
The study compared the efficacy of four treatment modalities for alopecia areata in 100 patients over one year. Patients were divided into four groups of 25, receiving intralesional steroids, cryotherapy, topical phenol, or spot phototherapy (NBUVB). Results showed that intralesional steroids were the most effective, with 88% of patients experiencing cosmetically acceptable hair regrowth, followed by cryotherapy (76%), phenol (52%), and phototherapy (36%). Nail changes, particularly pitting, were observed in 34% of patients. The study concluded that intralesional steroids were the most effective treatment, but all modalities could be considered, with further evaluation needed for NBUVB.
July 2021 in “Dermatology archives” Methotrexate may effectively and safely treat hair loss in children, with notable improvement after 12-15 months.
13 citations,
April 2020 in “Dermatology and therapy” Cyclosporine combined with corticosteroids is more effective for severe alopecia areata than cyclosporine alone.
January 2020 in “Indian Journal of Forensic Medicine & Toxicology” Oral cyclosporine is an effective and safe treatment for severe alopecia areata.
17 citations,
March 2018 in “Pediatric dermatology” Hydroxychloroquine may help treat alopecia areata in children.
38 citations,
January 2013 in “Dermatology” Careful patient selection is key for effective pulse corticosteroid treatment in children with alopecia areata.
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January 2012 in “International journal of trichology” Steroids are the best treatment for Alopecia Areata with few side effects.
37 citations,
November 2011 in “Photodermatology Photoimmunology & Photomedicine” Narrowband UVB phototherapy alone is not very effective for treating alopecia areata.
14 citations,
January 2011 in “International Journal of Trichology” Some people with severe, long-lasting baldness responded well to a specific combination treatment.
60 citations,
October 2009 in “PubMed” Intralesional steroid injections are safe and effective for treating severe alopecia areata.
36 citations,
May 2005 in “BMC dermatology” DPCP is effective for treating severe alopecia areata, but relapse is common.