TLDR Different types of scarring alopecia may be stages of one disease, and accurate diagnosis is crucial to prevent permanent hair loss.
The 2001 document reviews cicatricial (scarring) alopecia, detailing the clinical presentations, potential etiologies, and histopathologic features of various forms such as lichen planopilaris, pseudopelade, discoid lupus erythematosus, folliculitis decalvans, and others. It highlights the importance of histopathology and immunofluorescence in diagnosis, noting the difficulty in differentiating between early lesions of these conditions. The review suggests that different scarring alopecias may represent stages of a single disease process, emphasizing the need for accurate diagnosis through detailed history, laboratory data, and advanced techniques to prevent permanent hair follicle damage.
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158 citations
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February 2000 in “Archives of dermatology” Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.
12 citations
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January 2000 in “Journal of cutaneous medicine and surgery” Microorganism overgrowth and hyperkeratosis may trigger immune reactions causing lichen planopilaris.
44 citations
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November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
28 citations
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September 1998 in “Medical Clinics of North America” Most hair loss can be diagnosed with patient history and physical exam, and a few common types make up most cases.
329 citations
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January 1997 in “Journal of the American Academy of Dermatology” Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.
71 citations
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March 1995 in “Journal of The American Academy of Dermatology” Using both vertical and transverse sections for alopecia biopsies improves diagnosis without extra cost.
15 citations
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July 1975 in “British journal of dermatology/British journal of dermatology, Supplement” Graham-Little syndrome causes scarring hair loss and skin bumps.
