Chemically Induced Hair Loss Alopecia

    January 2012
    Howard I. Maïbach, Ian Yamaguchi
    TLDR Certain chemicals and drugs can cause hair loss.
    The document reviewed the impact of exogenous chemicals and drugs on hair loss, highlighting that increased hair shedding and thinning were common side effects. It discussed the mechanisms by which chemicals induce hair loss, such as precipitating telogen development or poisoning the anagen root, and the difficulty in proving chemical-induced alopecia. The chapter also covered various types of hair loss, including anagen and telogen, and listed specific chemicals and medications known to cause hair loss, such as antimitotic agents and antithyroid drugs. Additionally, it proposed animal and human assay models to study these effects and emphasized the need for further understanding of the pathobiology of hair follicle responses to chemotherapy.
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