Caffeine and Its Role in Regulation the Androgenetic Alopecia.
February 2021
TLDR Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
The review article "Caffeine and Its Role in Regulation the Androgenetic Alopecia" discusses the potential of caffeine in treating Androgenetic Alopecia (AGA), a common form of hair loss. AGA is primarily caused by the conversion of testosterone to dihydrotestosterone (DHT), which leads to hair follicle minimization and reduced hair density. Currently, only two FDA-approved drugs, finasteride and minoxidil, are available for AGA treatment. However, recent studies have shown that caffeine, a common ingredient in cosmetics, can counteract DHT-induced hair follicle minimization. Caffeine works by inhibiting the phosphodiesterase (PDE) enzyme, leading to increased intracellular concentrations of CAMP, which stimulates metabolic activity and improves cell proliferation. Various in vitro and in vivo studies, as well as clinical trials, have demonstrated the beneficial effects of caffeine against hair loss.
View this study on alqalam.utripoli.edu.ly →
Related
research Assessment of the Oxidative Stress Status in Androgenetic Alopecia in Egyptian Men
research Assessment of Human Nuclear Factor Erythroid 2 Related Factor 2 (NRF2) in Androgenetic Alopecia in Egyptian Men
research Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen
Impaired autophagy may cause hair loss by triggering early catagen.
research Androgenetic Alopecia: Clinical Treatment
research Androgenetic alopecia and its remedies – a review
research Cell Biology and Disease of Hair Follicle (2):Pathomechanism and Treatment of Androgenetic Alopecia
research Aging of hair and its treatment
research The Change of the Frontal Hair Line According to the Treatment for Androgenetic Alopecia
research Hair Loss Unrelated to Androgenetic Alopecia
research Apoptosis, Androgenetic Alopecia, and the Hair Cycle
research Towards a molecular understanding of hair loss and its treatment
Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.