Correlation Analysis of BLTP1 (KIAA1109) and KIF27 Gene Polymorphisms with Wool Traits in Subo Merino Sheep

    February 2026 in “ Genes
    Qingfa Yan, Sen Tang, Asma Anwar, Gvlnigar Amar, Yaqian Wang, Wenna Liu, Cuiling Wu, Xuefeng Fu
    TLDR BLTP1 and KIF27 gene mutations can help breed better wool sheep.
    This study on 944 Subo Merino sheep explores the impact of BLTP1 and KIF27 gene polymorphisms on wool traits. A missense mutation in the BLTP1 gene (SNP1) significantly affects wool crimp number and staple length, while a mutation in the KIF27 gene (SNP2) influences live weight after shearing. These mutations alter protein structures, suggesting their potential as molecular markers for breeding high-quality fine-wool sheep. The research highlights the genetic diversity at these loci and provides a theoretical basis for molecular breeding, aiming to improve wool quality and breeding efficiency.
    Discuss this study in the Community →