Bioinformatics Analysis and Verification of m6A Related Genes Based on the Construction of Keloid Diagnostic Model

This study investigates the relationship between m6A-related genes and keloid formation using bioinformatics methods. By analyzing transcriptomic datasets from keloid and normal skin tissues, the study identifies significant differences in the expression of m6A genes, particularly IGF2BP3, which is up-regulated in keloid patients. Six hub genes were identified through protein-protein interaction analysis, and their functions were linked to cell division, proliferation, metabolism, and immunity-related pathways. The study also examines immune cell infiltration in keloid tissues, providing insights into the molecular mechanisms and potential therapeutic targets for keloid treatment.