TLDR Dutasteride may help prevent prostate cancer, but more research is needed.
The authors acknowledged the limitations of their study design, which did not definitively prove the effectiveness of dutasteride in preventing prostate cancer. However, they highlighted the significant impact of dutasteride compared to finasteride, attributing this to dutasteride's ability to inhibit both type 1 and type 2 5-alpha-reductase, enzymes present in some prostate cancers. This finding suggested the need for further research on dutasteride's potential in cancer prevention. The document also compared the PCPT and REDUCE studies, noting differences in study duration, subject numbers, and enzyme inhibition.
June 2023 in “Clinica Chimica Acta” Finasteride and dutasteride effectively reduce DHT in hair, which may help evaluate their treatment success for hair loss.
19 citations
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April 2020 in “Dermatologic Therapy” Dutasteride works better than finasteride for hair loss, with both being safe to use.
August 2016 in “Journal of Investigative Dermatology”
January 2015 in “프로그램북(구 초록집)” Dutasteride is effective and safe for treating common hair loss, and it's more potent than finasteride, leading to better hair growth and thickness.
April 2013 in “The FASEB Journal” 219 citations
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October 2009 in “Steroids” 5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.
215 citations
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November 2006 in “Journal of The American Academy of Dermatology” Dutasteride more effective for hair growth, but has more side effects than finasteride.
33 citations
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October 2005 in “PubMed” Dutasteride successfully treated a woman's hair loss when other treatments failed.