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    Research 10 of 1000+

    1. Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta) Teratology · 1997 · 67 citations
    2. Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats Frontiers in Pharmacology · 2025 · 2 citations
    3. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    4. Risk of Type 2 Diabetes Mellitus in New Users of 5-Alpha Reductase Inhibitors: A Nationwide Historical Cohort Study Yonsei Medical Journal · 2026
    5. Luteinizing Hormone and Human Chorionic Gonadotropin Decrease Type 2 5α-Reductase and Androgen Receptor Protein Levels in Women’s Skin The Journal of Clinical Endocrinology & Metabolism · 1998 · 13 citations
    6. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    7. Absence of Interaction Between 5α‐Reductase Inhibitors and Glucocorticoids on Incidence of Myocardial Infarction in People With Type 2 Diabetes Diabetes Obesity and Metabolism · 2026
    8. 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH The Journal of Urology · 2010
    9. Sex dependent influence of a functional polymorphism in steroid 5‐α‐reductase type 2 (<i>SRD5A2</i>) on post‐traumatic stress symptoms American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 2013 · 35 citations
    10. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
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    Community 10 of 84

    1. 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that? Reddit · 3 Oct 2024
    2. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    3. Was scared to try fin and jumped straight to 2.5mg Dut? Reddit · 12 Sept 2026
    4. 5ar Type I in the frontal hair follicles - Dutasteride Reddit · 30 Apr 2024
    5. Thoughts on this Article: Post-Finasteride and Neurological Effects Reddit · 16 Mar 2024
    6. The truth about Dutasteride (w/ sources) Reddit · 24 Jan 2023
    7. Whats up with all the dutasteride destroying hair posts Reddit · 12 May 2023
    8. Connection between finasteride and nafld? Reddit · 13 Aug 2024
    9. DHT and 5AR respect post, it's importance within the brain Reddit · 3 Mar 2024
    10. Fun thought experiment about halting hair loss permamently Reddit · 6 May 2024
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    Learn 3 of 6

    1. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    2. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    3. Neem Oil Oil from the neem tree, used in traditional remedies
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