Association between Smoking and Hair Loss: Another Opportunity for Health Education against Smoking?

    January 2003 in “ Dermatology
    Ralph M. Trüeb
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    TLDR Smoking may contribute to hair loss in men.
    The document from 2003 discusses the potential link between smoking and hair loss, particularly androgenetic alopecia. It suggests that smoking may contribute to hair loss through various mechanisms such as damage to the microvasculature of the dermal hair papilla, DNA damage in hair follicle cells, imbalance in protease/antiprotease systems, oxidative stress causing micro-inflammation and fibrosis, and a hypo-oestrogenic state. The author proposes that public awareness of this link could serve as a strong health education tool, potentially more effective than the association of smoking with facial wrinkles or grey hair, since treatments for hair loss are limited. An observational study is mentioned, showing a significant relationship between smoking and baldness in men, but the data was insufficient to draw conclusions for women.
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    Cited in this study

    2 / results
      Molecular mechanisms of androgenetic alopecia

      research Molecular mechanisms of androgenetic alopecia

      229 citations ,   August 2002 in “Experimental Gerontology”
      AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
      Treatment of Hair Loss

      research Treatment of Hair Loss

      370 citations ,   September 1999 in “The New England Journal of Medicine”
      Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.


    8 / results