Antiandrogen Therapy of Acne, Hair Loss, and Hirsutism

The document discussed the hormonal influences on conditions like hirsutism, seborrhea, acne, and hair loss, highlighting the role of androgens produced by the adrenal glands and ovaries. It reviewed the therapeutic use of large doses of estrogen or gestagen since the 1960s, noting varying success. Significant advancements were achieved with the development of antiandrogenic progestogens, particularly cyproterone acetate, which provided satisfactory results for women when applied selectively based on clinical symptoms.