Anti-Androgenic Therapy as Chemoprevention of Prostate Cancer

    January 2004 in “ Medicina de Familia SEMERGEN ”
    D. Subirá Ríos, E. Alonso Sandoica, Juan Ignacio Martínez‐Salamanca, J. Jara Rascón, C. Hernández Fernández
    TLDR Finasteride may help prevent prostate cancer.
    The article discussed the potential role of 5-alpha-reductase inhibitors, such as finasteride, in the prevention of prostate cancer. It presented a case of prostatic intraepithelial neoplasm (PIN) treated with finasteride for benign prostatic hyperplasia, which resulted in prostatic atrophy upon biopsy. The study explored the mechanism of anti-androgenic therapy in treating dysplasias and reviewed existing literature on its potential to reduce prostate cancer risk.
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