Androgenetic Alopecia: An Attempt to Target Microinflammation
February 2020
in “
Dermatologic Therapy
”
![Image of study](/images/research/faa21a2a-f507-456f-956d-67620341ecda/medium/4743.jpg)
TLDR Reducing micro-inflammation didn't change hair growth patterns in AGA.
This letter to the editor discusses a study conducted on 60 men with androgenetic alopecia (AGA) to determine if reducing micro-inflammation around hair follicles would improve hair growth. The participants were randomized into two groups, one using minoxidil 5% solution and the other using a solution containing topical minoxidil and betamethasone dipropionate. Both groups showed significant hair growth, but reducing micro-inflammation did not alter hair growth patterns in AGA. The study suggests that while there is perifollicular lymphocytic infiltration on histopathology of scalp biopsies in AGA patients, none of the approved treatments affect the inflammation around hair follicles.
View this study on onlinelibrary.wiley.com →
Cited in this study
2 / results![The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis](/images/research/08482596-9ae3-460f-a65b-c2f5c78d8ab1/small/4080.jpg)
research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
![Histologic Response to Topically Applied Minoxidil in Male-Pattern Alopecia](/images/research/e4ab26c0-a0e9-4d52-8c95-59ffa45e1f98/small/1895.jpg)
research Histologic Response to Topically Applied Minoxidil in Male-Pattern Alopecia
Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.