An Update of Hair Shaft Disorders
October 1996
in “
Dermatologic clinics
”
hair shaft disorders congenital hair shaft abnormalities hereditary hair shaft abnormalities clinical characteristics microscopic characteristics topical selective gene therapy hair follicle faults molecular genetics clinical diagnostic criteria laboratory diagnostic criteria hair shaft anomalies increased fragility alopecia weathering process gene therapy hair follicle hair fragility hair loss
TLDR Advances in genetics may lead to targeted treatments for hair disorders.
The document discussed congenital and hereditary hair shaft abnormalities, emphasizing the clinical and microscopic characteristics that were well described many years ago. It highlighted the potential for targeted topical selective gene therapy for hair follicle faults due to advancements in molecular genetics. The document stressed the importance of up-to-date clinical and laboratory diagnostic criteria for well-known conditions and classified hair shaft anomalies into those with increased fragility, which present as alopecia, and those without. It also noted the significance of understanding the weathering process in assessing hair shaft disorders.
