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research Clinical Characteristics and Prognostic Factors in Early-Onset Alopecia Totalis and Alopecia Universalis

38 citations , January 2012 in “Journal of Korean Medical Science”

This study found that early-onset patients with alopecia universalis or a family history of alopecia areata showed worse prognosis compared to those with late-onset.

research Clinical characteristics and outcomes of adult patients admitted with COVID-19 in East London: a retrospective cohort analysis

35 citations , March 2021 in “BMJ Open Respiratory Research”

This study found that among patients hospitalized with COVID-19 in East London, ongoing symptoms were common, with 70% experiencing issues like fatigue and breathlessness, impacting their return to work.

research Clinical characteristics of polycystic ovary syndrome: investigating differences in White and South Asian women

29 citations , March 2015 in “Clinical Endocrinology”

This study found that women with polycystic ovary syndrome in the UK show significant differences in phenotypic and metabolic characteristics based on ethnicity, age, and obesity, influencing management strategies.

research Clinical characteristics in Taiwanese women with polycystic ovary syndrome

15 citations , January 2015 in “Clinical and Experimental Reproductive Medicine”

This study reports that obesity significantly influences cardiovascular and metabolic disturbances in women with PCOS, with overweight women experiencing more severe symptoms compared to their non-obese counterparts.

Clinical Characteristics, Trichoscopy, Histopathology, and Treatment Outcomes of Frontal Fibrosing Alopecia in an Asian Population: A Retro-Prospective Cohort Study

research Clinical characteristics, trichoscopy, histopathology and treatment outcomes of frontal fibrosing alopecia in an Asian population: A retro‐prospective cohort study

9 citations , July 2020 in “Journal of Dermatology”

This study found that diffuse and pseudo-fringe sign patterns are common in Asian patients with frontal fibrosing alopecia, and that treatments combining antiandrogens or antimalarials with topical therapy are effective.

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community My summation of PP405 - looks promising

210 upvotes 1 year ago

PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

community What is the cause of "DHT itch"?

in Research/Science 7 upvotes 1 year ago

The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.

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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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learn KY19382

Are there clinical studies showing that KY19382 can regrow hair in androgenic alopecia? No clinical studies have proven KY19382 regrows hair in androgenic alopecia.

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What do clinical trials say about the safety and effectiveness of SCUBE3 for hair regrowth? No clinical trial of SCUBE3 for hair regrowth has been registered on ClinicalTrials.gov or published, so there is no human safety or effectiveness data. The evidence is limited to one 2022 laboratory and mouse study reporting that SCUBE3 activates hair follicle stem cells through TGF-beta signalling.

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Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.

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What types of hair loss conditions are most commonly associated with tofacitinib use in clinical settings? Published studies link tofacitinib mainly to alopecia areata and its severe variants — as an off-label drug being studied for them, not as a cause of hair loss. The evidence is mostly small, open-label or retrospective, and relapse after stopping is commonly reported.

learn GT20029

When will GT20029 be commercially available, and are there any clinical trials on its use? GT20029 is not approved or commercially available anywhere and remains investigational. A published 12-week Phase II study in 180 Chinese men reports hair-count gains over placebo, but no long-term or Phase III data exists, so any launch is years away at best.

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research Clinical Characteristics and Prognostic Factors in Early-Onset Alopecia Totalis and Alopecia Universalis

research Clinical characteristics and outcomes of adult patients admitted with COVID-19 in East London: a retrospective cohort analysis

research Clinical characteristics of polycystic ovary syndrome: investigating differences in White and South Asian women

research Clinical characteristics in Taiwanese women with polycystic ovary syndrome

research Clinical characteristics, trichoscopy, histopathology and treatment outcomes of frontal fibrosing alopecia in an Asian population: A retro‐prospective cohort study

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community My summation of PP405 - looks promising

community What is the cause of "DHT itch"?

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

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learn Overview

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learn Stem Cell Factor

learn KY19382

learn SCUBE3

learn Follistatin

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learn GT20029

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