Alkyl Shikimates Promote Proliferation of Human Dermal Fibroblasts and Exhibit Structure–Activity Relationships

    June 2026 in “ Scientific Reports ”
    Hidetada Morishita, Koji Umezawa, Masanobu Kojima
    Studysummary This study found that alkyl shikimates with different alkyl group structures can increase or decrease fibroblast proliferation depending on concentration and alkyl chain length, with some variants showing cytotoxic effects due to their hydrophobicity and cell membrane permeability.
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