Activity and Safety of Cinchonine Nanostructured Lipid Carriers as a Hair Growth Stimulant in Mice Model of Androgenetic Alopecia

June 2023 in “ Sains Malaysiana ”

Hariyanti Hariyanti, Rachmat Mauludin Rachmat Mauludin, Yeyet C SUMİRTAPURA, Neng Fisheri Kurniati

Cinchonine Nanostructured Lipid Carriers CN-NLC hair growth stimulant androgenetic alopecia hair follicles dermal papillae Cinchonine NLC hair growth alopecia dermal papilla

TLDR Cinchonine Nanostructured Lipid Carriers serum safely and effectively stimulates hair growth and increases the number and size of hair follicles.

The study tested Cinchonine Nanostructured Lipid Carriers (CN-NLC) serum as a hair growth stimulant in a mice model of Androgenetic Alopecia. The serum was applied for 21 days, with measurements taken at 7, 14, and 21 days. The results showed hair length increased by 20.24-23.74% on day 7, 33.47-36.43% on day 14, and 39.30-39.97% on day 21. Additionally, the serum increased the number and size of hair follicles and dermal papillae. The study concluded that CN-NLC serum is safe and effective as a hair growth stimulant in the treatment of Androgenetic Alopecia.

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