Acquired Uncombable Hair Syndrome

    August 1993 in “ Archives of Dermatology
    C. A. Kuhn
    TLDR A 39-year-old woman developed uncombable hair syndrome after taking oral contraceptives.
    The document described the first documented case of acquired uncombable hair syndrome, also known as pili trianguli et canaliculi, in a 39-year-old healthy woman. This syndrome was characterized by dry, coarse hair with a spangled appearance and was previously known to be congenital, with over 50 cases reported and some suggesting an autosomal dominant inheritance. The woman experienced diffuse alopecia over three months, with hair loss on the vertex and crown, while taking a combination oral contraceptive. The case highlighted the unique presentation of acquired uncombable hair syndrome, expanding the understanding of this condition beyond its congenital form.
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