A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism

    March 2004 in “European journal of endocrinology
    Fahrettin Kelestimur, Hatice Everest, Kursad Unluhizarci, Fahri Bayram, Yilmaz Sahin
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    TLDR Spironolactone plus finasteride reduces hirsutism more effectively.
    This study compared the effectiveness and safety of spironolactone alone versus spironolactone plus finasteride in treating hirsutism in women. Both groups showed a significant reduction in hirsutism scores, but the combination therapy resulted in a more significant reduction. The study suggests that combined anti-androgen drugs with different mechanisms of action may be a useful therapy in the management of hirsutism.
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